Roberto Verardo graduated in Biological Sciences from the University of Trieste with an experimental thesis on the characterization of the promoter of a p53-induced gene. He then obtained a PhD in Clinical Sciences and Technologies from the University of Udine.
Roberto worked as researcher at the LNCIB Trieste, where he was involved in several projects on transcriptome characterization, including: the development of methodologies and protocols for the construction of full-length cDNA libraries and the characterization of the transcriptome of eukaryotic cells; the setup and optimization of microarray platforms for gene expression analyses in the field of cancer research; the development and optimization of simplified molecular assays and their integration into Point of Care diagnostic devices for in vitro molecular diagnostics (in collaboration with STMicroelectronics).
He was recently the scientific manager at Alphagenics Biotech Srl, a small biotech company, where he worked on the optimization and application of molecular diagnostic techniques, with emphasis on the development of simplified and rapid sample preparation procedures, as well as of molecular assays for the determination of gene signatures and mutation profiles.
His research focuses primarily on the field of molecular oncology and diagnostics with reference to various types of cancer, such as ovarian and breast cancer, as well as tumor-stroma interactions and the isolation and characterization of mesenchymal stem cells. Furthermore, he is interested in studying the definition of minimal bacterial signatures for microbiota characterization.
In collaboration with LNCIB, he has recently been involved in the development of fixation methods for ribonucleoprotein aggregates, to enable their subsequent compositional characterization. He has also been working on leveraging CRISPR-Cas for diagnostic purposes.
From October 2024 he is a researcher at the Laboratory of Genomics and Epigenomics (LAGE) in Area Science Park, Trieste.