X-ray Diffraction (XRD) with Synchrotron Radiation

Reveal the structural details of your proteins and small molecules using XRD with synchrotron radiation, through our collaboration with Elettra Sincrotrone Trieste.

Several experimental stations at Elettra are dedicated to X-ray diffraction studies and allow to investigate different aspects of material structure: XRD1 and XRD2 experimental stations are designed to obtain structural details at the atomic level from single crystals, while MCX beamline allows to perform a wide range of non-single crystal diffraction experiments.

XRD1 Beamline

XRD1 beamline hosts primarily small molecule crystallography experiments, with typical crystals of fewer than 100 atoms in the unit cell. Main objectives are crystal structure determination, molecular structure and geometry, ambient and non-ambient conditions, intermolecular interactions, and charge density studies.

XRD2 Beamline

XRD2 beamline is dedicated to high throughput macromolecular crystallography (MX) experiments which often involves up to tens of thousands of atoms in the unit cell. Crystals of proteins, DNA, RNA or complexes are analysed to obtain new 3D structures to help understand the function, locate interaction sites of interest and shed lights on interactions with small molecules in order to design potential pharmaceutical drugs.

MCX Beamline

MCX beamline performs X-ray powder diffraction experiments to obtain structural information on surface and solid-state properties. Systems that can be investigated vary from organic and inorganic materials, in the form of powders in capillaries or in intact formulations.

Visit Elettra website for more information.

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