Laser Capture Microdissection Microscope

Laser Capture Microdissection (LCM) (also known as Laser Microdissection or LMD) is a technology used to isolate specific single cells or entire areas of tissue using a UV laser. LMD is typically used in genomics (DNA), transcriptomics (mRNA, miRNA), proteomics, metabolomics, and even next generation sequencing (NGS). Furthermore, LMD is a perfect tool for live cell culture (LCC), for cloning and re-cultivation, manipulation or downstream analysis.
The Leica LMD7 is based on a fully automated research microscope and enables users to isolate and manipulate microscopic samples in a contact- and contamination-free manner. It has an adjustable high-powered laser with possibility to adjust the laser pulse frequency and laser head current for dissection of hard tissues like bone, teeth, wood or plant tissue as well as chromosomes.

• Fast, precise isolation of ultra-pure cells and cell populations.
• Real-time live cutting directly on the sample.
• Laser type: diode pumped, solid state.
• Wavelength: 349 nm.
• Full control of laser power, laser aperture, laser speed, laser frequency, and laser focus.
• Range of dedicated LMD objectives: 2.5x, 5x, 6.3x, 10x, 20x, 40x, 63x and 150x.
• UV offset freely adjustable and saved for each objective.
• Laser beam movement via optics, while sample remains fixed.
• No limitation of size or shape of dissectate.
• Fully integrated fluorescence: live cutting within brightfield and fluorescence.
• Collection devices: standard PCR tube caps 0.2 ml/0.5 ml.
• Different cutting modes and drawing tools to either dissect and pool or separate specimens of different sizes and shapes.