Laser Capture Microdissection Microscope

Leica LMD7

Laser Capture Microdissection (LCM) (also known as Laser Microdissection or LMD) is a technology used to isolate specific single cells or entire areas of tissue using a UV laser. LMD is typically used in genomics (DNA), transcriptomics (mRNA, miRNA), proteomics, metabolomics, and even next generation sequencing (NGS). Furthermore, LMD is a perfect tool for live cell culture (LCC), for cloning and re-cultivation, manipulation or downstream analysis.
The Leica LMD7 is based on a fully automated research microscope and enables users to isolate and manipulate microscopic samples in a contact- and contamination-free manner. It has an adjustable high-powered laser with possibility to adjust the laser pulse frequency and laser head current for dissection of hard tissues like bone, teeth, wood or plant tissue as well as chromosomes.

  • Fast, precise isolation of ultra-pure cells and cell populations.
  • Real-time live cutting directly on the sample.
  • Laser type: diode pumped, solid state.
  • Wavelength: 349 nm.
  • Full control of laser power, laser aperture, laser speed, laser frequency, and laser focus.
  • Range of dedicated LMD objectives: 2.5x, 5x, 6.3x, 10x, 20x, 40x, 63x and 150x.
  • UV offset freely adjustable and saved for each objective.
  • Laser beam movement via optics, while sample remains fixed.
  • No limitation of size or shape of dissectate.
  • Fully integrated fluorescence: live cutting within brightfield and fluorescence.
  • Collection devices: standard PCR tube caps 0.2 ml/0.5 ml.
  • Different cutting modes and drawing tools to either dissect and pool or separate specimens of different sizes and shapes.

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