Quantitative Intermolecular Interaction Characterization

The facility provides complementary techniques to measure affinity, kinetic binding constants, stoichiometry and all the thermodynamics binding parameters (ΔH, ΔS and ΔG).

📍The quantitative intermolecular interaction characterization services are provided by CNR-IOM and Elettra Sincrotrone Trieste laboratories in Area Science Park.

Selected Publications

• “Targeting Siderophore-Mediated Iron Uptake in M. abscessus: A New Strategy to Limit the Virulence of Non-Tuberculous Mycobacteria”
  M. Mori et al., Pharmaceutics 2023, 15(2), 502
  DOI: doi.org/10.3390/pharmaceutics15020502
• “Molecular architecture of the glycogen- committed PP1/PTG holoenzyme”
  M.S. Semrau et al., Nature Communications, 2022, 13, 6199
  DOI: 10.1038/s41467-022-33693-z