The “Structural Biology Platform” offers instrumentation and expertise for preparation, purification and characterization of samples, different in size and nature. It is based on modern core facilities devoted to the production of mg-scale pure protein samples and to the synthesis of gram-scale bioactive compounds. It is a platform for hits and leads identification, according to a structure-based drug discovery approach for the development of bioactive, low-molecular mass molecules against previously identified targets.
The platform offers users the most advanced preparation, purification, and biochemical-biophysical characterization tools for the purposes of largescale high-purity sample production, integrated with a highly automated crystallization station and high-throughput small molecules synthesis laboratory.